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Published on: June 21, 2017
Manganese-Mediated Coupling Reaction of Vinylarenes and Aliphatic Alcohols
Wei Zhang1, Nai-Xing Wang1, Cui-Bing Bai1
1Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Abstract:
Alcohols and alkenes are the most abundant and commonly used organic building blocks in the large-scale chemical synthesis. Herein, this is the first time to report a novel and operationally simple coupling reaction of vinylarenes and aliphatic alcohols catalyzed by manganese in the presence of TBHP (tert-butyl hydroperoxide). This coupling reaction provides the oxyalkylated products of vinylarenes with good regioselectivity and accomplishes with the principles of step-economies. A possible reaction mechanism has also been proposed.
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