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Updated: Mar 31, 2026

Rapid Characterization of Genetic Parts with Cell-Free Systems
Published on: August 30, 2021
Industrialization of Biology
Douglas C Friedman1, Andrew D Ellington2
1Board on Chemical Sciences and Technology, National Academies of Sciences, Engineering, and Medicine , Washington, DC 20003, United States.
Abstract:
The advancement of synthetic biology over the past decade has contributed substantially to the growing bioeconomy. A recent report by the National Academies highlighted several areas of advancement that will be needed for further expansion of industrial biotechnology, including new focuses on design, feedstocks, processing, organism development, and tools for testing and measurement; more particularly, a focus on expanded chassis and end-to-end design in an effort to move beyond the use of E. coli and S. cerivisiea to organisms better suited to fermentation and production; second, continued efforts in systems biology and high-throughput screening with a focus on more rapid techniques that will provide the needed information for moving to larger scale; and finally, work to accelerate the building of a holacratic community with collaboration and engagement between the relevant government agencies, industry, academia, and the public.
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