Access to Functionalized Luminescent Multi-2,2':6',2″-terpyridine Ligands

Area of Science:

• Supramolecular Chemistry
• Organic Synthesis
• Coordination Chemistry

Background:

• Terpyridines are versatile ligands in coordination chemistry.
• Multi-terpyridine systems are crucial for constructing complex supramolecular architectures.
• Efficient synthesis of functionalized multi-terpyridines remains a challenge.

Purpose of the Study:

• To develop a facile one-pot synthesis for substituted multi-2,2′:6′,2″-terpyridines (multi-tpy).
• To explore the scalability of the synthesis towards larger terpyridine structures.
• To demonstrate the utility of these multi-tpy units as building blocks for supramolecular assemblies.

Main Methods:

• One-pot condensation of an acetylquaterpyridine precursor with aryl aldehydes in basic media.
• Suzuki-type cross-coupling reactions for extending terpyridine frameworks.
• Characterization of synthesized multi-terpyridine compounds.

Main Results:

• Successful synthesis of functionalized tri-terpyridines via a one-pot method.
• Preparation of tetra- and hexa-terpyridine structures through cross-coupling reactions.
• Demonstrated accessibility of diverse and complex multi-tpy architectures.

Conclusions:

• The developed method provides efficient access to functionalized multi-terpyridines.
• The synthesized multi-tpy units serve as valuable building blocks for supramolecular chemistry.
• This strategy facilitates the construction of advanced metal-based supramolecular assemblies.