Visible-Light-Catalyzed Direct Benzylic C(sp(3))-H Amination Reaction by Cross-Dehydrogenative Coupling
Ganesh Pandey1, Ramkrishna Laha2
1Molecular Synthesis Laboratory, Centre of Bio-Medical Research (CBMR), Sanjay Gandhi Postgraduate Institute of Medical Science Campus Raebareli Road, Lucknow-226014 (India). gp.pandey@cbmr.res.in.
Abstract:
A conceptually new and synthetically valuable cross-dehydrogenative benzylic C(sp(3))-H amination reaction is reported by visible-light photoredox catalysis. This protocol employs DCA (9,10-dicyanoanthracene) as a visible-light-absorbing photoredox catalyst and an amide as the nitrogen source without the need of either a transition metal or an external oxidant.
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