Related Experiment Video

Updated: Mar 31, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

9.6K

Differential T-cell subset representation in cutaneous squamous cell carcinoma arising in immunosuppressed versus

Laurence Feldmeyer1,2, Grace Ching3, Harina Vin3

  • 1Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Experimental Dermatology
|October 18, 2015
PubMed
Abstract

No abstract available in PubMed .

Keywords:
NanoStringT cellcutaneous squamous cell carcinomagene expression profilingimmunohistochemistryimmunosuppression

More Related Videos

Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model
07:49

Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model

Published on: April 13, 2015

21.1K
Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
08:32

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Published on: June 7, 2018

10.5K

Related Experiment Videos

Last Updated: Mar 31, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

9.6K
Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model
07:49

Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model

Published on: April 13, 2015

21.1K
Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
08:32

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Published on: June 7, 2018

10.5K

Related Concept Videos

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

17.4K
T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
17.4K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

86.4K
Overview
86.4K
T Cell Types and Functions01:24

T Cell Types and Functions

3.3K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
3.3K

Articles linked to this work by shared authors, journal, and citation graph.

Cutaneous reactions to modern systemic oncologic therapies: a histopathological and clinical review.

Histopathology·2026

UV signature mutation hyperhotspots as genomic dosimeters.

Photochemistry and photobiology·2026

In vivo Tracking of Clonal Dynamics in UV-Induced Skin Carcinogenesis Reveals Tumor Development from Goliath Clades.

Cancer research·2026

Eruptive Acral Melanocytic Lesions Associated With Capecitabine.

Journal of cutaneous pathology·2026

Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer.

Cell·2026

Immunologic determinants of infusion products and the tumor microenvironment govern response to TIL therapy in advanced melanoma.

Med (New York, N.Y.)·2026

The Spatiotemporal Coupling Imbalance of Senescent Grey Hair: Remodelling of the HFSC-MeSC-Niche Network and a New Paradigm of Stem Cell Senescence.

Experimental dermatology·2026

Chronic Spontaneous Urticaria and Psychiatric Symptoms: The Blood-Brain Barrier Hypothesis.

Experimental dermatology·2026

Keratinocyte Autophagy in Inflammatory Dermatoses: Mechanisms, Disease-Specific Programs and Therapeutic Opportunities.

Experimental dermatology·2026

When Cold Gets Under the Skin: An Immunometabolic Circuit in Psoriasis.

Experimental dermatology·2026

mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation.

Experimental dermatology·2026

Selective Expansion of TCR Vβ2+ Tregs and Impaired Lymphocyte TSST-1 Responsiveness in Bullous Pemphigoid Patients Colonised by Staphylococcus aureus.

Experimental dermatology·2026

Jugulotympanic paraganglioma, preoperative embolization, and transmastoid retrolabyrinthine approach: Two-dimensional operative video.

Surgical neurology international·2026

Immunosenescence in tumor progression: from synergistic mechanisms to therapeutic strategies.

Critical reviews in oncology/hematology·2026

The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review.

Medical oncology (Northwood, London, England)·2026

CAR T cell-induced interferon gamma enhances MHC class I expression and sensitizes neuroblastoma to TCR-engineered T cell therapy.

Frontiers in immunology·2026

Noninvasive immune-inflammatory profiling by ultrasound radiomics for preoperative prediction of central lymph node metastasis in papillary thyroid carcinoma.

Frontiers in immunology·2026

Non-immune regulation of tertiary lymphoid structures in cancer.

Frontiers in immunology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us