[The relationship between platelet count and mean platelet volume with obstructive sleep apnea syndrome]

This study aims to investigate the relationship between platelet count and mean platelet volume (MPV) with obstructive sleep apnea syndrome (OSAS).

This retrospective study included 417 OSAS patients (284 males, 133 females; mean age 47.9±10.0; range 23 to 75 years) who were performed polisomnography (PSG) in our clinic between January 2013 and December 2014. Patients were divided into two groups according to apnea-hipopnea index (AHI). Apnea-hipopnea index <5 was assumed as normal, while AHI ≥5 was assumed as OSAS. Platelet count and MPV values of group with normal AHI and group with OSAS were statistically compared. Apnea-hipopnea index, REM AHI, non-REM AHI, minimum oxygen saturation, and duration of oxygen saturation remaining below 90% were statistically compared with platelet count and MPV.

The mean of platelet count in non-OSAS and OSAS groups were 262.31±65.78 and 252.77±61.86, respectively, with no statistically significant difference between the groups. Mean platelet volume in non-OSAS and OSAS groups were 9.56±1.88 and 9.71±1.57, respectively; however, the difference was not statistically significant. Platelet count increased statistically significantly as AHI, REM AHI, non-REM AHI, and minimum oxygen saturation parameters got impaired.

As PSG parameters get impaired, platelet count increases in OSAS patients.