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Successful Management of a Chronic Refractory Leg Ulcer in an Adolescent with Sickle Cell Anemia
Giovanni Paolino1, Michelina Santopietro, Giovanna Palumbo
1Giovanni Paolino, MD, Clinica Dermatologica, La Sapienza University of Rome, Viale del Policlinico 15, 00186 Rome, Italy; gio8519@libero.it.
Abstract:
Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by a wide range of clinical manifestations. Chronic leg ulcers are a disabling complication with repercussions on the quality of life. We report the case of a 14-year-old girl with a diagnosis of SCD who developed a chronic leg ulcer that was successfully treated with a multi-disciplinary approach, including local and systemic therapies. The role of different treatments, in particular low molecular weight heparin, in the refractory chronic leg ulcer healing process will be discussed.
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