Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simplified rat lung transplantation using a cuff technique.

T Mizuta1, A Kawaguchi, K Nakahara

  • 1First Department of Surgery, Osaka University Medical School, Japan.

The Journal of Thoracic and Cardiovascular Surgery
|April 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tracheostomy, respiratory support, and developmental outcomes in neonates with severe lung diseases: Retrospective study in one center.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2020
Same author

Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development.

Nature communications·2019
Same author

Measurement of thickness of film deposited on the plasma-facing wall in the QUEST tokamak by colorimetry.

The Review of scientific instruments·2017
Same author

Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity.

Journal of virology·2016
Same author

Survey of volume CT dose index in Japan in 2014.

The British journal of radiology·2015
Same author

Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization.

Clinical and experimental immunology·2013
Same journal

Pushing the Age Limit: Mitral Valve Surgery Is Safe and Effective in Octogenarians.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Bridging Pediatric and Young Adult Cancer Survivorship: Defining the Thoracic Surgeon's Role Across the Continuum.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Beyond compensatory expansion: Extending 3-dimensional computed tomography volumetry toward lung-preserving local therapy.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

A CALL FOR STANDARDIZATION OF HYBRID ARCH FROZEN ELEPHANT TRUNK OUTCOMES REPORTING.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Pediatric Mitral Valve Surgery: Current Practice from the European Congenital Heart Surgeons Association Congenital Database Analysis.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Rethinking Failure to Rescue in Cardiac Surgery.

The Journal of thoracic and cardiovascular surgery·2026
See all related articles

A novel cuff technique for rat lung transplantation significantly reduces graft ischemic and operating times. This method demonstrates high survival rates and excellent graft function, improving oxygenation in transplanted lungs.

Area of Science:

  • Surgical Innovation
  • Transplantation Research
  • Cardiovascular Surgery

Background:

  • Lung transplantation is a complex procedure with challenges in vascular anastomosis.
  • Minimizing ischemia and operative time is crucial for graft survival and function.
  • Previous techniques for pulmonary vein and artery anastomosis in rats are time-consuming.

Purpose of the Study:

  • To introduce and evaluate a novel cuff technique for pulmonary vein and artery anastomosis in rat lung transplantation.
  • To assess the impact of this technique on graft ischemic time and overall operating time.
  • To determine the short-term survival rate and graft function following transplantation using the cuff technique.

Main Methods:

  • A cuff technique was developed for performing vascular anastomoses in rat lung transplantation.

Related Experiment Videos

  • The technique was applied in 11 consecutive rat lung transplantation cases.
  • Graft ischemic time, operating time, and postoperative survival were recorded and analyzed.

    • Main Results:

    • The average graft ischemic time was 13.5 ± 2.0 minutes, significantly less than previous reports.
    • The average operating time was 100.7 ± 4.8 minutes, approximately half of previous methods.
    • Excluding operative deaths, the survival rate was 88.8% (8/9) by postoperative day 11.
    • Contralateral pneumonectomy confirmed excellent graft function and adequate animal oxygenation.

    Conclusions:

    • The cuff technique offers a more efficient method for pulmonary vein and artery anastomosis in rat lung transplantation.
    • This technique substantially reduces critical ischemic and operative times, potentially improving outcomes.
    • The high survival rate and demonstrated graft function support the efficacy of this innovative surgical approach.