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Is It Better to Be Rich or Relaxed? Sociobiology Meets Bone Marrow Transplant
Lucie M Turcotte1, Michael R Verneris2
1Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Abstract:
Low socioeconomic status in hematopoietic cell transplant recipients is associated with increased treatment-related mortality and relapse, resulting in reduced survival. No biologic mechanism has been identified for these associations. The stress-related gene expression profile, termed the "conserved transcriptional response to adversity," may be a predictor of these negative outcomes.
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