Related Experiment Video

Updated: Mar 31, 2026

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.6K

Sleep disorders in pediatric chronic kidney disease patients

Stella Stabouli1, Eleni Papadimitriou2, Nikoleta Printza2

  • 1Pediatric Nephrology Unit, 1st Pediatric Department, Hippokration Hospital, Aristotle University of Thessaloniki, 49 Konstantinoupoleos Street, 54642, Thessaloniki, Greece. sstaboul@auth.gr.

Pediatric Nephrology (Berlin, Germany)
|October 21, 2015
PubMed

Insights

Children with chronic kidney disease (CKD) have a high prevalence of sleep disorders, significantly impacting their health-related quality of life (HRQOL). Early identification and management of these sleep issues are crucial for improving patient outcomes.

Area of Science:

  • Pediatric Nephrology
  • Sleep Medicine
  • Quality of Life Research

Background:

  • Sleep disorders are common in childhood, affecting 25-43% of the pediatric population.
  • Chronic kidney disease (CKD) may exacerbate sleep disturbances in children.
  • Health-related quality of life (HRQOL) is a critical outcome measure in pediatric chronic conditions.

Purpose of the Study:

  • To determine the prevalence of sleep disorders in children with CKD.
  • To explore associations between sleep disorders and CKD-related factors.
  • To assess the impact of sleep disorders on HRQOL in pediatric CKD patients.

Main Methods:

  • Systematic literature search of PubMed, Embase, and Cochrane Library Databases.
  • Inclusion of seven relevant studies focusing on sleep disorders in children with CKD.
  • Assessment of sleep disturbances primarily through questionnaires, with one study using polysomnography.

Main Results:

  • All reviewed studies reported an increased prevalence of sleep disorders in children with CKD.
  • Prevalence of sleep disorders ranged from 32-85% depending on CKD status (dialysis, transplant, non-dialysis).
  • Restless legs syndrome was the most common disorder (10-35%); sleep disorders were linked to reduced HRQOL.

Conclusions:

  • Children with CKD exhibit a significantly higher prevalence of sleep disorders.
  • Sleep disturbances are associated with poorer HRQOL in this vulnerable pediatric population.
  • Further research and clinical attention to sleep issues in pediatric CKD are warranted.

Keywords:
ChildrenChronic kidney diseaseDaytime sleepinessHealth-related quality of lifeRestless legs syndromeSleep

More Related Videos

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

6.2K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.9K

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
625
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
612
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
957
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1.2K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
374
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
781