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Updated: Mar 31, 2026
Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
Published on: April 30, 2019
Cell biology of the future: Nanometer-scale cellular cartography
1Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 justin.taraska@nih.gov.
Abstract:
Understanding cellular structure is key to understanding cellular regulation. New developments in super-resolution fluorescence imaging, electron microscopy, and quantitative image analysis methods are now providing some of the first three-dimensional dynamic maps of biomolecules at the nanometer scale. These new maps--comprehensive nanometer-scale cellular cartographies--will reveal how the molecular organization of cells influences their diverse and changeable activities.
