A New Etiology for the Abdominal Compartment Syndrome: Pseudomyxoma Peritonei

Charles Sabbagh1, Colette Vaillandet1, Jean-Jacques Tuech2

  • 1Department of Digestive and Metabolic Surgery, Amiens University Hospital, University of Picardie Jules Verne, Amiens, France.

Insights

Pseudomyxoma peritonei (PMP) is rare. Abdominal compartment syndrome in PMP patients is manageable with surgery and chemotherapy, offering a chance for long-term survival without recurrence.

Area of Science:

  • Oncology
  • Gastroenterology
  • Surgical Pathology

Background:

  • Pseudomyxoma peritonei (PMP) is a rare malignancy originating typically from appendiceal rupture, characterized by mucin accumulation in the peritoneal cavity.
  • PMP progression can lead to bowel obstruction and cutaneous fistulas, with abdominal compartment syndrome being an infrequent but severe complication.

Observation:

  • This case report details a patient diagnosed with PMP who developed abdominal compartment syndrome.

Findings:

  • Initial management involved laparotomy to alleviate abdominal pressure.
  • Subsequent treatment included peritonectomy combined with hyperthermic intraperitoneal chemotherapy.
  • The patient remained disease-free one year post-treatment, indicating successful management.

Implications:

  • Acute abdominal pain and respiratory distress in PMP patients warrant abdominal pressure measurement.
  • Abdominal compartment syndrome is not a contraindication for curative PMP treatment.
  • Aggressive surgical and chemotherapeutic approaches can achieve long-term remission in complex PMP cases.

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