A New Etiology for the Abdominal Compartment Syndrome: Pseudomyxoma Peritonei
Charles Sabbagh1, Colette Vaillandet1, Jean-Jacques Tuech2
1Department of Digestive and Metabolic Surgery, Amiens University Hospital, University of Picardie Jules Verne, Amiens, France.
Abstract:
Pseudomyxoma peritonei (PMP) is a rare diagnosis with an incidence of 1-2 per million. Most cases originate from an appendix which ruptures and releases mucin into the peritoneal cavity. The progression of the disease results in obstruction and cutaneous leak. Abdominal compartment syndrome is an uncommon complication of peritoneal pseudomyxoma. In the present article, we report the case of a patient with PMP and abdominal compartment syndrome. A laparotomy to decrease the abdominal pressure was performed. Three months later, a peritonectomy with hyperthermic intraperitoneal chemotherapy was performed. The patient was still alive 1 year after the procedure without any recurrence. In conclusion, acute abdominal pain and respiratory failure in patients with peritoneal PMP should lead to the measurement of the abdominal pressure but are not a contra indication for curative treatment of PMP.
Insights
Pseudomyxoma peritonei (PMP) is rare. Abdominal compartment syndrome in PMP patients is manageable with surgery and chemotherapy, offering a chance for long-term survival without recurrence.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Pseudomyxoma peritonei (PMP) is a rare malignancy originating typically from appendiceal rupture, characterized by mucin accumulation in the peritoneal cavity.
- PMP progression can lead to bowel obstruction and cutaneous fistulas, with abdominal compartment syndrome being an infrequent but severe complication.
Observation:
- This case report details a patient diagnosed with PMP who developed abdominal compartment syndrome.
Findings:
- Initial management involved laparotomy to alleviate abdominal pressure.
- Subsequent treatment included peritonectomy combined with hyperthermic intraperitoneal chemotherapy.
- The patient remained disease-free one year post-treatment, indicating successful management.
Implications:
- Acute abdominal pain and respiratory distress in PMP patients warrant abdominal pressure measurement.
- Abdominal compartment syndrome is not a contraindication for curative PMP treatment.
- Aggressive surgical and chemotherapeutic approaches can achieve long-term remission in complex PMP cases.
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