Related Experiment Video

Updated: Mar 31, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.9K

Management of chronic kidney disease-mineral and bone disorder: Korean working group recommendations

Eunah Hwang1, Bum Soon Choi2, Kook-Hwan Oh3

  • 1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.

Kidney Research and Clinical Practice
|October 21, 2015
PubMed

Insights

Korean dialysis patients face significant burdens from chronic kidney disease-mineral bone disorder. This study proposes practical recommendations for managing abnormal serum phosphorus, calcium, and intact parathyroid hormone (iPTH) levels.

Area of Science:

  • Nephrology
  • Endocrinology
  • Bone Metabolism

Background:

  • Chronic kidney disease-mineral bone disorder (CKD-MBD) poses a significant threat to Korean dialysis patients, linked to cardiovascular calcification and mortality.
  • Epidemiologic data reveal many patients on maintenance hemodialysis fall outside target ranges for serum calcium, phosphorus, and intact parathyroid hormone (iPTH).

Purpose of the Study:

  • To address the need for practical recommendations for managing abnormal serum phosphorus, calcium, and iPTH in dialysis patients.
  • To propose simplified medication adjustment strategies for optimal management of secondary hyperparathyroidism.

Main Methods:

  • Review of current practices regarding measurement of serum calcium, phosphorus, and iPTH.
  • Discussion of dialysate calcium concentration, dietary phosphorus restriction, and phosphate binders.
  • Evaluation of medical and surgical options for correcting secondary hyperparathyroidism.

Main Results:

  • A simplified medication adjustment strategy is suggested based on serum phosphorus and calcium levels for managing secondary hyperparathyroidism.
  • Current management practices and options are briefly commented upon.

Conclusions:

  • Development of practical recommendations is necessary for treating abnormal mineral and bone metabolism in dialysis patients.
  • Large-scale clinical studies are required to validate proposed strategies and establish practice guidelines for improved patient outcomes.

Keywords:
CalciumDialysisPhosphorusSecondary hyperparathyroidism

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

5.4K
Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.9K

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
625
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
612
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
957
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
479
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
686
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1.2K