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Updated: Mar 31, 2026

Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR
Published on: May 29, 2014
Data in brief: Transcriptome analysis of induced pluripotent stem cells from monozygotic twins discordant for trisomy
Youssef Hibaoui1, Iwona Grad2, Audrey Letourneau3
1Stem Cell Research Laboratory, Department of Obstetrics and Gynecology, Geneva University Hospitals, 30 bd de la Cluse, CH-1211 Geneva, Switzerland ; Department of Genetic Medicine and Development, University of Geneva Medical School and Geneva University Hospitals, 1 rue Michel-Servet, CH-1211 Geneva, Switzerland.
Abstract:
Down syndrome (DS, trisomy 21), is the most common viable chromosomal disorder, with an incidence of 1 in 800 live births. Its phenotypic characteristics include intellectual impairment and several other developmental abnormalities, for the majority of which the pathogenetic mechanisms remain unknown. In this "Data in Brief" paper, we sum up the whole genome analysis by mRNA sequencing of normal and DS induced pluripotent stem cells that was recently published by Hibaoui et al. in EMBO molecular medicine.
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