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Published on: July 20, 2022
Left Ventricular Assist Device Driveline Infections: The Achilles' Heel of Destination Therapy
1Marc Angud is Adult-Gerontology Acute Care Nurse Practitioner Student, Thomas Jefferson University College of Nursing, 901 Walnut Street, Suite 823, Philadelphia, PA 19107 (marc.angud@jefferson.edu).
Insights
Heart failure affects millions, often requiring advanced treatments like left ventricular assist devices (LVADs). Infection risk is a significant concern with these external devices.
Area of Science:
- Cardiology
- Medical Devices
- Infectious Disease
Background:
- Heart failure impacts millions, necessitating advanced interventions beyond medical management.
- Heart transplantation is limited by donor organ availability.
- Left ventricular assist devices (LVADs) are increasingly used for advanced heart failure, serving as a bridge to transplant or a long-term solution.
Purpose of the Study:
- To highlight the growing importance of LVADs in managing end-stage heart failure.
- To identify infection as a primary concern associated with current LVAD technology.
Main Methods:
- Review of current literature on heart failure management and LVADs.
- Analysis of the technological aspects of LVADs, focusing on the percutaneous driveline.
Main Results:
- LVADs are crucial for patients with end-stage heart failure due to donor heart scarcity.
- The external power source and percutaneous driveline of LVADs present a significant pathway for infection.
Conclusions:
- LVADs offer a vital treatment option for advanced heart failure.
- Addressing and mitigating infection risks associated with LVAD drivelines is critical for patient outcomes.
Abstract:
Heart failure is a chronic progressive disease that affects millions of people in the United States. Although medical management of heart failure has helped improve quality of life and survival, end-stage heart failure ultimately requires a heart transplant or long-term left ventricular assist device (LVAD) support. With more patients awaiting transplant, the demand for hearts outweighs the supply of donor hearts. The use of LVADs is increasing in patients with advanced heart failure as a treatment option for those awaiting a heart transplant or as a long-term solution if they are ineligible for a transplant. Although the LVAD is a marvel of modern medicine, infection is a cause of concern because today's LVADs are powered externally through a percutaneous driveline that can be a major source of infection.
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