Related Experiment Video
Updated: Mar 31, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Diagnosis of hepatitis C virus genotype 2k/1b needs NS5B sequencing
Steven De Keukeleire1, Patrick Descheemaeker1, Marijke Reynders1
1Department of Laboratory Medicine, Clinical Microbiology, AZ St-Jan Bruges-Ostend, Ruddershove 10, 8000 Bruges, Belgium.
Abstract:
Hepatitis C virus (HCV) is probably the most common cause of liver cirrhosis and hepatocellular carcinoma worldwide. The correct identification of HCV genotype has important clinical implications as a marker of responsiveness to antiviral therapy and serves as a guideline for the duration of treatment. The VERSANT HCV Genotype 2.0 Assay failed to detect HCV genotype 2k/1b. HCV genotype 2k/1b detection requires NS5B sequencing.
Related Concept Videos
Hepatitis
Viruses with RNA Genomes

