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Kikuchi-Fujimoto disease: pediatric case report
Eduardo Ojeda Lewis1, Héctor Vásquez Paz2
1Servicio de pediatría, Hospital Nacional Dos de Mayo de Lima, Ministerio de Salud, Lima, Perú. Address: Hospital Hipólito Unanue, Calle Blondel s/n, Cercado de Tacna, Perú.
Medwave
|October 21, 2015
Summary
Kikuchi-Fujimoto disease, a rare condition causing fever and swollen lymph nodes, can affect children. This case highlights its prolonged presentation, emphasizing its importance in pediatric differential diagnoses.
Area of Science:
- Pediatrics
- Pathology
- Immunology
Background:
- Kikuchi-Fujimoto disease (KFD) is a rare, benign, and self-limited disorder.
- KFD typically affects young adults with symptoms of fever and cervical lymphadenopathy.
- The exact etiology of KFD remains unknown, complicating diagnosis.
Observation:
- A 9-year-old girl presented with prolonged fever and lymphadenopathy for five months.
- This represents the longest documented duration of KFD symptoms in pediatric literature.
- Clinical presentation can mimic other serious conditions, posing diagnostic challenges.
Findings:
- The case underscores the rarity of KFD in pediatric populations.
- Histopathological features are crucial for differentiating KFD from other lymphadenopathies.
- Prolonged symptoms in children necessitate careful consideration of KFD.
Implications:
- Pediatricians should include KFD in the differential diagnosis for children with prolonged fever of unknown origin.
- Increased awareness of KFD in children can lead to earlier diagnosis and appropriate management.
- Further research into KFD etiology and presentation in children is warranted.

