Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Determination of Crystal Structures01:29

Determination of Crystal Structures

58
In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...
58
Polymer Classification: Crystallinity01:21

Polymer Classification: Crystallinity

4.2K
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
4.2K
Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

5.8K
Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

Physical review letters·2022
Same author

The role of tissue type, sampling and nucleic acid purification methodology on the inferred composition of Pacific oyster (Crassostrea gigas) microbiome.

Journal of applied microbiology·2019
Same author

A retrospective study of past graduates of a residential life skills program for youth with physical disabilities.

Child: care, health and development·2014
Same author

A four-part ecological model of community-focused therapeutic recreation and life skills services for children and youth with disabilities.

Child: care, health and development·2012
Same author

A citation analysis of the influence on research of Skinner's verbal behavior.

The Behavior analyst·2012
Same journal

50, 100 & 150 Years: Natural fission reactor uncovered; geometry of soap bubbles.

Scientific American·2026
Same journal

Academic Freedom in Decline: When scientists can't research what they want, innovation suffers.

Scientific American·2026
Same journal

Robots Can Now Fold Your Laundry: Home-helper tasks are becoming easier for robotic assistants.

Scientific American·2026
Same journal

Journey to Titan: Inside NASA's Dragonfly mission to Saturn's largest moon.

Scientific American·2026
Same journal

Getting Pesticides Off Fruits and Veggies: Using more than water to wash produce can clean pesticide residues.

Scientific American·2026
Same journal

How Probability Theory Got Its Start: Disagreement over how to divvy up the pot in an interrupted game of chance led early mathematicians to invent modern risk assessment.

Scientific American·2026
See all related articles

Related Experiment Video

Updated: Mar 24, 2026

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline
09:00

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline

Published on: June 17, 2021

3.5K

Macromolecular crystals.

A McPherson1

  • 1Department of Biochemistry, University of California, Riverside.

Scientific American
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

X-ray crystallography reveals large molecule structures. Producing high-quality protein or nucleic acid crystals is essential but challenging for this powerful technique.

More Related Videos

Optimization of Crystal Growth for Neutron Macromolecular Crystallography
12:29

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Published on: March 13, 2021

6.0K
Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography
18:45

Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography

Published on: September 2, 2012

25.8K

Related Experiment Videos

Last Updated: Mar 24, 2026

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline
09:00

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline

Published on: June 17, 2021

3.5K
Optimization of Crystal Growth for Neutron Macromolecular Crystallography
12:29

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Published on: March 13, 2021

6.0K
Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography
18:45

Harvesting and Cryo-cooling Crystals of Membrane Proteins Grown in Lipidic Mesophases for Structure Determination by Macromolecular Crystallography

Published on: September 2, 2012

25.8K

Area of Science:

  • Structural Biology
  • Biophysics

Background:

  • X-ray crystallography is a key method for determining the three-dimensional structure of biomacromolecules.
  • Understanding molecular structure is crucial for deciphering biological function and disease mechanisms.

Purpose of the Study:

  • To highlight the critical role of crystal quality in X-ray crystallography.
  • To emphasize the challenges associated with obtaining suitable crystals for structural analysis.

Main Methods:

  • The abstract focuses on the prerequisite of crystal formation for X-ray crystallography.
  • It implies the use of X-ray diffraction principles for structural determination.

Main Results:

  • The primary requirement for successful X-ray crystallography is the availability of nearly flawless crystals.
  • Crystal perfection is identified as a significant bottleneck in the technique.

Conclusions:

  • The feasibility of X-ray crystallography is directly dependent on the ability to produce high-quality crystals.
  • Further research may be needed to improve methods for crystal growth.