Related Experiment Video
Updated: Mar 31, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Limb-shaking transient ischemic attacks: Two case reports with unusual pathogenesis
Abstract:
Limb-shaking transient ischemic attacks are associated with transient regional cerebral hypoperfusion and severe carotid stenosis. We report two patients with unusual pathogenesis of limb-shaking attacks, one a 73-year-old woman with right-sided limb-shaking attacks and normal carotid angiography (recently diagnosed with essential thrombocytosis, antiplatelet agents eliminated her attacks) and the other a 56-year-old woman with peptic ulcer disease and multiple episodes of left-sided limb-shaking. Severe anemia was found along with bilateral carotid stenoses >70%. Correction of her anemia abolished her limb-shaking episodes. The presumed pathogenesis of limb-shaking transient ischemic attacks is transient focal cerebral ischemia from severe occlusive disease. Our two patients demonstrate that the mechanisms of ischemia may include other factors that affect oxygen delivery such as anemia or platelet disorders.
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Peripheral Artery Disease I: Introduction
Venous Thrombosis I: Introduction
Coronary Artery Disease II: Pathophysiology
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Dysrhythmias II: Classification of Tachyarrhythmias

