Related Experiment Video

Updated: Mar 31, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K

Encephalitis-Associated Human Metapneumovirus Pneumonia in Adult, Australia

Anthony Fok, Cristina Mateevici, Belinda Lin

    Emerging Infectious Diseases
    |October 22, 2015
    PubMed

    Insights

    Human metapneumovirus pneumonia, typically seen in children, occurred in an adult with encephalitis. Consider testing for this virus in adults with encephalitis and prior respiratory illness.

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Virology

    Background:

    • Human metapneumovirus (hMPV) is a common respiratory pathogen, primarily affecting children.
    • Encephalitis is a serious neurological condition characterized by inflammation of the brain.

    Observation:

    • A case of encephalitis in an adult was diagnosed with human metapneumovirus pneumonia.
    • The adult patient presented with symptoms suggestive of a preceding respiratory infection.

    Findings:

    • Human metapneumovirus RNA was detected in both nasopharyngeal aspirate and cerebrospinal fluid samples.
    • This finding establishes a link between hMPV infection and encephalitis in an adult.

    Implications:

    • The findings suggest that hMPV should be considered in the differential diagnosis of adult encephalitis, especially following respiratory illness.
    • Diagnostic testing for hMPV in cerebrospinal fluid and respiratory samples may be warranted in such cases.
    • This highlights the potential for hMPV to cause severe neurological disease beyond its typical pediatric respiratory manifestations.
    Keywords:
    AustraliaParamyxoviridaeencephalitishuman metapneumoviruspneumoniaviruses

    More Related Videos

    A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness12:21

    A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

    Published on: September 28, 2022

    3.3K
    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay09:14

    An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

    Published on: January 26, 2019

    11.6K

    Related Concept Videos

    Atypical Pneumonia01:14

    Atypical Pneumonia

    Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
    38
    Pneumonia I: Introduction01:30

    Pneumonia I: Introduction

    Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
    Risk Factors
    Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
    1.3K
    Viral Meningitis01:18

    Viral Meningitis

    Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
    96
    Arboviral Encephalitis01:25

    Arboviral Encephalitis

    Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
    25
    Pneumonia II: Pathophysiology01:29

    Pneumonia II: Pathophysiology

    The pathophysiology of pneumonia involves the following steps:
    4.1K
    Pneumonia V: Nursing management and Prevention01:30

    Pneumonia V: Nursing management and Prevention

    Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
    The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
    Enhance airway patency
    Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
    4.0K