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Related Concept Videos

Insomnia01:27

Insomnia

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Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
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Insufficient Sleep and Sleep Deprivation01:13

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Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
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Management of Insomnia01:19

Management of Insomnia

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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
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Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

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Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
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Sleep-Wake Cycles01:24

Sleep-Wake Cycles

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Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
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Insomnia Symptoms Are Associated With Abnormal Endothelial Function.

Faye S Routledge1, Sandra B Dunbar, Melinda Higgins

  • 1Faye S. Routledge, PhD, RN Assistant Professor, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Sandra B. Dunbar, PhD, RN Professor, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Melinda Higgins, PhD Associate Professor, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Ann E. Rogers, PhD, RN Professor, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Christine Feeley, PhD, RN Assistant Professor, School of Nursing, University of Pittsburg Medical Center, Pennsylvania. Octavian Ioachimescu, PhD, MD Associate Professor, Atlanta Veterans Affairs Medical Center and Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, Georgia. Kristina Euwer, MD Medical House Staff, University of Pittsburg Medical Center, Pennsylvania; and School of Medicine, Emory University, Atlanta, Georgia. Danny Eapen, MD Assistant Professor, School of Medicine, Emory University, Atlanta, Georgia. Arshed Quyyumi, MD Professor, School of Medicine, Emory University, Atlanta, Georgia.

The Journal of Cardiovascular Nursing
|October 22, 2015
PubMed
Summary
This summary is machine-generated.

Insomnia symptoms are linked to poorer endothelial function, a key indicator of cardiovascular health. This suggests a potential mechanism connecting sleep disturbances to increased heart disease risk.

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Area of Science:

  • Cardiovascular Health
  • Sleep Science
  • Endothelial Function

Background:

  • Insomnia is a common sleep disorder linked to cardiovascular disease.
  • Endothelial dysfunction may mediate the relationship between insomnia and cardiovascular risk.
  • This study investigated the association between insomnia symptoms and endothelial function.

Purpose of the Study:

  • To test the hypothesis that insomnia symptoms are associated with reduced endothelial function.
  • To explore the link between subjective sleep quality and objective measures of vascular health.

Main Methods:

  • 496 working adults completed questionnaires on sleep, depression, and anxiety.
  • Noninvasive endothelial function was assessed using brachial artery flow-mediated dilation (FMD).
  • Insomnia symptoms were defined by sleep latency, awakenings, or medication use frequency.

Main Results:

  • 39.5% of participants reported insomnia symptoms.
  • Insomnia symptoms were inversely associated with FMD after adjusting for confounders.
  • Participants with insomnia had significantly lower FMD compared to those with better sleep.

Conclusions:

  • Insomnia symptoms are associated with impaired endothelial function.
  • Further research is needed to explore the impact of insomnia treatment on endothelial function and cardiovascular outcomes.