[Hypoglycemia caused by cibenzoline. Apropos of a new case]

The rare cases of hypoglycemia reported during treatment with cibenzoline, have been observed with drug overdoses, in combination with kidney failure, and with ECG signs of drug intoxication. A case report involving an 80 year old man is presented. He had a moderate degree of kidney failure and was on high drug dosage, considering his age and weight. Nevertheless, serum concentrations of cibenzoline were normal, and the QRS wave was not widened on the ECG. The hypothesis of an individual susceptibility to this agent is postulated. The absence of any ECG changes is emphasized. Monitoring of blood sugar is routinely required in patients treated with cibenzoline.