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The captopril test: an aid to investigation of hypertension
C E Daman Willems1, V Shah, M Uchiyama
1Renal Unit, Hospital for Sick Children, London.
Archives of Disease in Childhood
|February 1, 1989
Abstract:
Twenty three children aged from 5 to 16 with mild to moderate hypertension were investigated using the orally active angiotensin converting enzyme inhibitor captopril. Falls in both systolic and diastolic blood pressure after a single dose of captopril were significantly correlated with initial plasma renin activity. In addition, some information about the aetiology of hypertension was deduced from the renin response to captopril. The blood pressure response to captopril is a useful screening test for renin dependent hypertension in childhood.