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Updated: Mar 31, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
Facial asymmetry assessment in adults using three-dimensional surface imaging
Arti Patel1, Syed Mohammed Shamsul Islam2, Kevin Murray3
1Department of Orthodontics, School of Dentistry, The University of Western Australia, 35, Stirling Hwy, Crawley, Western Australia, 6009, Australia. arts_patel@hotmail.com.
Background:
The use of three-dimensional (3D) surface imaging is becoming more popular and accepted in the fields of Medicine and Dentistry. The present study aims to develop a technique to automatically localise and quantify soft-tissue asymmetry in adults using 3D facial scans. This may be applied as a diagnostic tool to monitor growth and dynamic changes and to evaluate treatment outcomes.
Methods:
3D facial surface data were captured from 55 adults comprising 28 symmetrical faces and 27 asymmetrical faces using a 3dMDface system. A landmark-independent method, which compared the original and the mirrored 3D facial data, was developed to quantify the asymmetry. A Weibull distribution-based probabilistic model was generated from the root-mean-square (RMS) error data for the symmetrical group to designate a level of asymmetry which represented a normal range.
Results:
Statistically significant (p < 0.0001) differences in the RMS error values were found when comparing symmetrical with asymmetrical groups and a similarly significant difference was identified between the lower and the upper face of the asymmetrical group.
Conclusions:
The proposed 3D imaging-based method of identifying and quantifying facial soft-tissue asymmetry was fast and effective. The Weibull distribution-based comparison of a person's asymmetry with respect to a large sample of symmetrical faces may also be used to evaluate growth, soft-tissue compensations and surgical outcomes.
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