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Updated: Mar 31, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
A rare case describing catastrophic destruction of the whole skeleton caused by severe hyperparathyroidism
Burcu Esen Akkas1, Busra Bedriye Demirel1, Elif Nisa Unlu2
1Department of Nuclear Medicine, Ankara Oncology Research and Training Hospital, Ankara, Turkey.
Abstract:
Osteitis fibrosa cystica is a skeletal disorder seen in advanced stages of persistent hyperparathyroidism. Although the measurement of serum Ca and intact-parathormone levels provides early diagnosis and decreases the incidence of radiographic bone involvement, progressive major bone lesions may still be seen in developing countries even in the modern era. We aimed to share, by writing up this report, our astonishment after observing how the skeletal system can be ruined by persistent hyperparathyroidism.
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