FGF23 in Acute and Chronic Illness
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Updated: Mar 31, 2026

Induction of an Inflammatory Response in Primary Hepatocyte Cultures from Mice
Published on: March 10, 2017
Christian Schnedl1, Astrid Fahrleitner-Pammer2, Peter Pietschmann3
1Division of Vascular and Interventional Radiology, Department of Radiology, Medical University of Graz, 8036 Graz, Austria.
Abstract:
FGF23 is a bone-derived phosphaturic hormone that may become a useful biomarker for the identification of high-risk patients in chronic but also acute disease. It rises early in chronic kidney disease and is strongly and independently associated with excess morbidity and mortality. Emerging data suggest that FGF23 is also elevated in different scenarios of acute illness. In this review, we give an overview on the role of this interesting disease marker and potential and proven interventional strategies and discuss a blueprint for future research.
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