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Sarcoidosis presenting as orbital pseudotumor
S Kobak1, A Topaloglu, G Öncel
1Department of Rheumatology, Sifa University, Faculty of Medicine, Izmir. senolkobak@gmail.com.
Reumatismo
|October 24, 2015
Summary
Sarcoidosis, a systemic inflammatory disease, can affect the lacrimal gland and cause eye problems. This case study details the diagnosis and treatment of a female patient with unilateral lacrimal gland swelling and muscle involvement due to sarcoidosis.
Area of Science:
- Ophthalmology
- Rheumatology
- Pathology
Background:
- Sarcoidosis is a systemic inflammatory disease of unknown cause, marked by non-caseating granulomas.
- Ocular involvement occurs in 25-60% of sarcoidosis patients, sometimes as the initial presentation.
- Lacrimal gland involvement is a recognized, though less common, manifestation of sarcoidosis.
Observation:
- A female patient presented with significant unilateral lacrimal gland swelling.
- The patient also exhibited musculoskeletal symptoms.
- Ocular examination revealed findings consistent with inflammatory processes.
Findings:
- Diagnostic workup, including imaging and laboratory tests, supported systemic inflammation.
- Histopathological examination confirmed non-caseating granulomas, characteristic of sarcoidosis.
- The patient was diagnosed with sarcoidosis involving the lacrimal gland and musculoskeletal system.
Implications:
- This case highlights the importance of considering sarcoidosis in the differential diagnosis of unilateral lacrimal gland swelling, especially with concurrent systemic symptoms.
- Early and accurate diagnosis is crucial for appropriate management and prevention of further organ damage.
- Multidisciplinary collaboration between ophthalmology, rheumatology, and pathology is essential for optimal patient care in complex sarcoidosis cases.
