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Related Experiment Video

Updated: Mar 31, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
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Retinal vessel structure measurement using spectral-domain optical coherence tomography.

T H Rim1, Y S Choi2, S S Kim1

  • 1Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea.

Eye (London, England)
|October 24, 2015
PubMed
Summary

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Spectral-domain optical coherence tomography (SD-OCT) reliably measures retinal vessel lumen diameters and wall thicknesses. Inner wall thickness measurements showed better reproducibility than outer wall measurements using SD-OCT.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Imaging

Background:

  • Spectral-domain optical coherence tomography (SD-OCT) is an advanced imaging technique.
  • Accurate measurement of retinal vessel dimensions is crucial for diagnosing and monitoring various ocular diseases.

Purpose of the Study:

  • To evaluate the reliability and validity of SD-OCT for measuring retinal vessel lumen diameters and wall thicknesses.
  • To assess the reproducibility of these measurements.

Main Methods:

  • SD-OCT was utilized to analyze the peripapillary region in 40 eyes from 20 subjects.
  • Retinal vessel lumen diameters and wall thicknesses (inner and outer) were quantified using intensity graphs.

Main Results:

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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
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Last Updated: Mar 31, 2026

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Doppler Optical Coherence Tomography of Retinal Circulation
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Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
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  • Mean arterial and venous luminal diameters were 95.1±16.1 μm and 132.6±17.8 μm, respectively.
  • Significant differences were observed in inner and outer wall thicknesses for both arteries and veins (P<0.01).
  • Intra- and interobserver intraclass correlation coefficients (ICCs) for lumen and wall thickness measurements were generally high (>0.85), with outer wall thickness showing the lowest reproducibility.

    • Conclusions:

    • SD-OCT, aided by intensity graphs, offers objective vessel boundary detection.
    • Measurements of luminal diameters and wall thicknesses using SD-OCT demonstrate good overall reproducibility.
    • Caution is advised when relying solely on outer wall thickness measurements due to lower reproducibility compared to inner wall measurements.