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Updated: Mar 31, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
Next-generation sequencing and empowering personalised cancer medicine
1Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
Abstract:
The announcement earlier this year of the US$1000 genome by Illumina has excited a debate as to when and how genomes will at last transition from the research laboratory to the clinic. Although it is still unclear what the benefit will be to patients, there is sufficient evidence supporting the importance of the genome in driving cancer development, treatment response and drug resistance. Therefore it is reasonable to assume that large-scale stratification of patients using next-generation sequencing technologies will improve patient outcome in at least some common cancer types.
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