Related Experiment Video
Updated: Mar 31, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
The Healthy Activity Program lay counsellor delivered treatment for severe depression in India: systematic
Neerja Chowdhary1, Arpita Anand1, Sona Dimidjian1
1Neerja Chowdhary, MD, Sangath, Goa, India and London School of Hygiene & Tropical Medicine, London, UK; Arpita Anand, MSc, MA, Sangath, Goa, India; Sona Dimidjian, PhD, University of Boulder, Boulder, Colorado, USA; Sachin Shinde, MPA, Sangath, Goa, India; Benedict Weobong, PhD, Sangath, Goa, India and London School of Hygiene & Tropical Medicine, London, UK; Madhumitha Balaji, MSc, Sangath, Goa, India; Steve D. Hollon, PhD, Vanderbilt University, Nashville, Tennessee, USA; Atif Rahman, PhD, University of Liverpool, Liverpool, UK; G. Terence Wilson, PhD, Rutgers University, New Brunswick, New Jersey, USA; Helena Verdeli, PhD, Teachers College, Columbia University, New York, USA; Ricardo Araya, PhD, London School of Hygiene & Tropical Medicine, London, UK; Michael King, PhD, University College, London, UK; Mark J. D. Jordans, PhD, King's College, London, UK; Christopher Fairburn, PhD, Oxford University, Oxford, UK; Betty Kirkwood, PhD, London School of Hygiene & Tropical Medicine, London, UK; Vikram Patel, FMedSi, Sangath, Goa, Centre for Chronic Conditions and Injuries, Public Health Foundation of India, New Delhi, India and London School of Hygiene & Tropical Medicine, London, UK.
Background:
Reducing the global treatment gap for mental disorders requires treatments that are economical, effective and culturally appropriate.
Aims:
To describe a systematic approach to the development of a brief psychological treatment for patients with severe depression delivered by lay counsellors in primary healthcare.
Method:
The treatment was developed in three stages using a variety of methods: (a) identifying potential strategies; (b) developing a theoretical framework; and (c) evaluating the acceptability, feasibility and effectiveness of the psychological treatment.
Results:
The Healthy Activity Program (HAP) is delivered over 6-8 sessions and consists of behavioral activation as the core psychological framework with added emphasis on strategies such as problem-solving and activation of social networks. Key elements to improve acceptability and feasibility are also included. In an intention-to-treat analysis of a pilot randomised controlled trial (55 participants), the prevalence of depression (Beck Depression Inventory II ⩾19) after 2 months was lower in the HAP than the control arm (adjusted risk ratio = 0.55, 95% CI 0.32-0.94,P= 0.01).
Conclusions:
Our systematic approach to the development of psychological treatments could be extended to other mental disorders. HAP is an acceptable and effective brief psychological treatment for severe depression delivered by lay counsellors in primary care.
Related Concept Videos
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Depression: Overview
Electroconvulsive Therapy
Cognitive Therapy
Specialized Care Centers and Settings-I
Daycare centers
They provide several functions. Some facilities care for healthy newborns and children whose parents work, while others are medically focused and care for...
Long-term Depression
Calcium Ion Concentration Mechanism
If over...

