[CARDIOVASCULAR DISEASES AS A RISK FACTOR OF CHRONIC GLOMERULONEPHRITIS PROGRESS]

Area of Science:

• Nephrology
• Cardiology
• Internal Medicine

Context:

• Cardiovascular diseases (CVD) frequently coexist with chronic glomerulonephritis (CGN).
• Understanding the impact of CVD on CGN progression is crucial for patient management.
• The study investigated the clinical course and outcomes of CGN patients with and without CVD.

Purpose:

• To evaluate the effect of concomitant cardiovascular diseases (CVD) on the progression of chronic glomerulonephritis (CGN).
• To compare renal function and survival rates in CGN patients with and without CVD.
• To assess the impact of combined CGN and CVD on liver function and survival.

Summary:

• Patients with CGN and concurrent CVD exhibited significantly higher serum creatinine levels and reduced glomerular filtration rates compared to those with CGN alone.
• The presence of CVD in CGN patients led to a significant decrease in 5- and 7-year survival rates.
• Combined CGN and CVD negatively affected nitrogen excretion and reduced liver survival rates in the pre-dialysis stage.

Impact:

• Highlights the detrimental effect of cardiovascular comorbidities on chronic kidney disease progression.
• Emphasizes the need for integrated management of CGN and CVD to improve patient prognosis.
• Suggests that early detection and treatment of CVD in CGN patients may mitigate adverse outcomes and improve survival.