Variability in Pancreatitis Care in Pediatrics: A Single Institution's Survey Report

Maisam Abu-El-Haija1, Joseph J Palermo, Lin Fei

  • 1From the *Division of Pediatric Gastroenterology, Hepatology and Nutrition and †Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Pancreas
|October 27, 2015
PubMed

Insights

Pediatric acute pancreatitis (AP) management lacks consensus among specialists. Developing evidence-based guidelines is crucial for consistent treatment of childhood AP.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Practice Patterns
  • Acute Pancreatitis Management

Background:

  • Childhood acute pancreatitis (AP) incidence has risen.
  • Current AP management in children largely relies on adult studies.
  • Lack of pediatric-specific treatment consensus exists.

Purpose of the Study:

  • To assess treatment consensus for acute pancreatitis (AP) among pediatric subspecialists.
  • To identify variations in managing uncomplicated AP in children.

Main Methods:

  • Survey of pediatric subspecialists managing AP admissions.
  • Analysis of practice patterns for diagnostic evaluation, fluid resuscitation, pain management, and nutrition.
  • Data collected from November 2009 to August 2013.

Main Results:

  • Significant variability in AP management practices was observed.
  • Practices differed between and within subspecialty groups.
  • Gastroenterology and hospitalist services admitted most AP patients.

Conclusions:

  • A consensus on managing acute uncomplicated pancreatitis in children is lacking.
  • Development of evidence-based pediatric guidelines is recommended.
  • Standardized guidelines can improve consistency in pediatric AP care.
Abstract

Related Concept Videos

Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
490
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.1K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.5K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
890
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
732
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
332