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Human bocavirus in children with acute gastroenteritis in Albania

G La Rosa1, S Della Libera1, M Iaconelli1

  • 1National Institute of Health, Department of Environment and Primary Prevention, Rome, Italy.

Journal of Medical Virology
|October 27, 2015
PubMed

Insights

Human Bocavirus (HBoV) was found in 9.1% of children with acute viral gastroenteritis (AGE) in Albania. Co-infections suggest HBoV may not be a primary cause of diarrhea, requiring further study.

Area of Science:

  • Virology
  • Pediatrics
  • Infectious Diseases

Background:

  • Human Bocavirus (HBoV) is a recently identified virus associated with acute viral gastroenteritis (AGE).
  • Understanding the prevalence of HBoV in different geographical regions is crucial for assessing its public health impact.

Purpose of the Study:

  • To determine the prevalence of Human Bocavirus (HBoV) in Albanian children diagnosed with acute viral gastroenteritis (AGE).

Main Methods:

  • Analysis of stool specimens from 142 children with AGE.
  • Detection of HBoV by amplification of partial NP1 and Vp1/Vp2 genes.

Main Results:

  • HBoV was detected in 13 out of 142 samples (9.1% prevalence).
  • The detected strains were predominantly HBoV-1 (12 samples) and one HBoV-2.
  • All HBoV-positive children had co-infections with rotavirus and/or adenovirus.

Conclusions:

  • The study identified HBoV in Albanian children with AGE, with HBoV-1 being the most common type.
  • Co-infections observed in all positive cases raise questions about HBoV's direct causal role in childhood diarrhea.
  • Further research is necessary to elucidate the pathogenic significance of HBoV in pediatric gastroenteritis.

Keywords:
epidemiologyfecal contaminantparvoviruspathogenesissheddingvirus classification

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