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Asthma in pregnancy.

¹University of Texas Health Science Center, San Antonio.

The Medical Clinics of North America

|May 1, 1989

Summary

This summary is machine-generated.

Pregnancy alters respiratory physiology, increasing ventilation. Acute asthma management remains largely unchanged, with most standard medications safe for pregnant patients.

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Area of Science:

Obstetrics and Gynecology
Pulmonology
Pharmacology

Background:

Pregnancy significantly impacts maternal respiratory physiology.
Understanding these changes is crucial for managing respiratory conditions during pregnancy.

Purpose of the Study:

To outline key respiratory physiological changes during pregnancy.
To review the safety and efficacy of acute asthma management in pregnant individuals.

Main Methods:

Review of physiological adaptations in pregnancy.
Analysis of medication safety profiles for asthma treatment during gestation.

Main Results:

Increased minute-ventilation and tidal volume, decreased functional residual volume, and reduced arterial pCO2 are characteristic of pregnancy.

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Beta-adrenergic agonists, theophylline, and glucocorticoids are safe and non-teratogenic for managing asthma in pregnancy.

Iodides are contraindicated; ephedrine and combination theophylline products should be avoided due to availability of better alternatives.

Conclusions:

Asthma management in pregnancy requires awareness of physiological changes but generally follows non-pregnant protocols.
Specific medication choices are critical, prioritizing safety and efficacy for both mother and fetus.