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Renal-type clear cell carcinoma of the prostate: a diagnostic challenge
Shashikant C U Patne1, Nidhi Johri2, Richa Katiyar3
1Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, UP, India. scupatne@gmail.com.
Abstract:
A 72-year-old male presented with urinary symptoms. His serum prostate specific antigen level was 65.2 ng/ml. His radical prostatectomy specimen showed clear cell lesion reminiscent of the clear cell renal cell carcinoma along with acinar type of prostatic adenocarcinoma, Gleason score 4 + 4. The lesional clear cells were positive for pancytokeratin, epithelial membrane antigen, CD10, vimentin, and AMACR while negative for 34βE12, CK7, prostate specific antigen, and PAX8. The final diagnosis was renal-type clear cell carcinoma of the prostate. A follow-up of 20 months did not show metastasis. We herein report fifth case of renal-type clear cell carcinoma of the prostate.
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