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Toxoplasma gondii seroprevalence: 30-year trend in an HIV-infected US military cohort
Thomas A O'Bryan1, Jason F Okulicz2, William P Bradley3
1Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Abstract:
To determine if Toxoplasma gondii IgG antibody prevalence is declining in HIV-infected persons, we analyzed data (1984-2013) from the US Military HIV Natural History Study. We found that T. gondii seroprevalence at enrollment was associated with age and decreased significantly after 1995 (P=0.004), similar to the general US population.