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Study of Ion Transfer Coupling with Electron Transfer by Hydrophilic Droplet Electrodes
Jing Gu1, Wenbo Zhao1, Ye Chen1
1Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University , Beijing 100871, China.
Abstract:
In a hydrophilic droplet three-electrode system, electroactive species within the droplet play very important roles in the electron-transfer (ET) process on the solid/electrolyte interface, which can then induce an ion-transfer (IT) reaction at the liquid/liquid interface. In this work, several redox couples and electroactive species are chosen to study ET-IT coupling processes at the water/1,2-dichloroethane (W/DCE) interface by cyclic voltammetry (CV) and Osteryoung square wave voltammetry (OSWV). Among them, the redox couple Ru(NH3)6(3+/2+) has been found to have the widest useful potential window of about 1.2 V. A hydrophilic droplet three-electrode system using a single electroactive molecule instead of a redox couple has been confirmed to be stable and has similar functionality to a redox couple. In addition, the lipophilicity of antiplatelet drug clopidogrel at the W/DCE interface is investigated and its ionic partition diagram has been constructed. Protonated clopidogrel is detected in a linear concentration range of 5.0-50 μM and the limit of detection (LOD) is calculated to be 3.0 μM by using the hydrophilic droplet system Ru(NH3)6(3+/2+) and OSWV.
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