Related Experiment Video
Updated: Mar 31, 2026
A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
Published on: March 17, 2023
A ratiometric two-photon fluorescent probe for hydrazine and its applications
Shenglong Yu1, Shuxin Wang1, Haizhu Yu1
1Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Abstract:
A ratiometric two-photon fluorescent probe TNQ was developed based on quinoline platform to detect hydrazine (N2H4) with high selectivity. TNQ exhibited large two-photon absorption cross sections at 710 nm (250 GM) and excellent ratiometric two-photon fluorescent detection signal for hydrazine. TNQ was also successfully applied to selectively detect hydrazine vapor even at a concentration down to 0.05%. Cell cytotoxicity and bio-imaging studies revealed that probe TNQ was cell-permeable and could be used to detect hydrazine in living cells with low cytotoxicity under two-photon excitation.
