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Feeding Intolerance and Poor Growth in Infants with Gastroschisis: Longitudinal Experience with Consecutive Patients

Saloni Balgi1, Sarita Singhal2, Georgia Mueller3

  • 1Department of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois.

Journal of Neonatal Surgery
|October 27, 2015
PubMed

Insights

Infants with gastroschisis often experience delayed full enteral nutrition and poor growth. Preterm infants are at higher risk, and aggressive feeding may contribute to these outcomes.

Area of Science:

  • Neonatalogy
  • Pediatric Surgery
  • Nutritional Science

Background:

  • Gastroschisis is a congenital defect requiring complex nutritional management.
  • Optimizing enteral nutrition and growth is critical for infant outcomes.

Purpose of the Study:

  • To identify in-hospital factors linked to delayed full enteral feeding in gastroschisis.
  • To evaluate the longitudinal growth patterns of infants with gastroschisis.

Main Methods:

  • Retrospective single-center study of 52 infants with gastroschisis over 13.5 years.
  • Data collected on demographics, nutrition, growth, and outcomes.
  • Linear regression analysis to determine factors associated with feeding intolerance and growth.

Main Results:

  • Median time to full feeds was 22 days; longer time correlated with increased hospital stay and weight gain.
  • Preterm birth was negatively associated with in-hospital weight gain.
  • 35% of infants had weight below the 5th percentile, with 67% of these being preterm.

Conclusions:

  • Many infants with gastroschisis exhibit poor growth, potentially exacerbated by aggressive feeding advancement.
  • Preterm infants with gastroschisis face a greater risk of suboptimal growth.
Abstract

Keywords:
Enteral nutritionGastroschisisGrowthPreterm infant

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