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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
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NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences01:17

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

2.0K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
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Physics and applications of positron beams in an integrated PET/MR.

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Injected dose in pediatric PET.

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Related Experiment Video

Updated: Mar 31, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
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A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

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The dynamics of physics in PET.

Charles C Watson1

  • 1Siemens Healthcare, 810 Innovation Drive, Knoxville, TN, 37932, USA. charles.c.watson@siemens.com.

EJNMMI Physics
|October 27, 2015
PubMed
Summary

Two forces, clinical needs and technical innovation, drive advancements in positron emission tomography (PET) instrumentation. Balancing these drivers is key for optimal progress in nuclear medicine technology.

Area of Science:

  • Medical Imaging
  • Nuclear Medicine Physics

Background:

  • Instrumentation in nuclear medicine, particularly positron emission tomography (PET), is evolving.
  • The development is influenced by both clinical requirements and technological advancements.

Purpose of the Study:

  • To analyze the interplay between clinical needs and technical innovation in PET instrumentation.
  • To discuss the impact of these forces on physics-related developments in PET.

Main Methods:

  • Conceptual analysis of the driving forces in PET instrumentation evolution.
  • Review of physics-related developments in the context of clinical and technical motivations.

Main Results:

  • Identified clinical needs and technical innovation as the two primary drivers of PET instrumentation evolution.
Keywords:
InstrumentationNuclear medicinePETPhysics

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Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
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  • Examined the dynamics of these forces on physics-related advancements.
  • Conclusions:

    • Progress in PET technology is maximized when clinical needs and technical innovation are maintained in equilibrium.
    • A balanced approach is recommended for the future evolution of nuclear medicine instrumentation.