Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Measurement of Bioavailability: Pharmacodynamic Methods

Measurement of Bioavailability: Pharmacodynamic Methods

Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.

Drug Products: Biologics, Biosimilars and Interchangeables

Drug Products: Biologics, Biosimilars and Interchangeables

Body:Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...

Biopharmaceutics and Pharmacokinetics: Overview

Biopharmaceutics and Pharmacokinetics: Overview

Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...

Bioequivalence: Overview

Bioequivalence: Overview

Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...

Drug Control Governance: Regulatory Bodies and Their Impact

Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cost-Utility Analysis of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.

Ophthalmology. Retina·2023

Same author

Prevention Surpasses Treatment: 5-year Follow-Up, Cost-Utility, and Cost-Benefit of Zeaxanthin Therapy for Neovascular Age-Related Macular Degeneration.

Ophthalmology and therapy·2023

Same author

Preference-based comparison of quality of life associated with vision loss in Black and White ophthalmic populations in the US.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2022

Same author

Quality of life associated with no light perception vision.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2022

Same author

Re: Le et al.: Associations between age-related eye diseases and Charles Bonnet Syndrome in participants of the Age-Related Eye Disease Study 2: Report Number 26 (Ophthalmology. 2022;129:233-235).

Ophthalmology·2022

Same author

Rural-Urban Comparisons in the Rates of Self-Harm, U.S., 2018.

American journal of preventive medicine·2022

Search research articles

Related Experiment Videos

Value-Based Medicine and Pharmacoeconomics.

Gary C Brown, Melissa M Brown

Developments in Ophthalmology

|October 27, 2015

Summary

Pharmacoeconomic analysis, particularly cost-utility analysis, is vital for healthcare policy. Value-based medicine (VBM) standardizes this analysis, enabling comparable assessments of drug value and financial impact for patients and society.

Area of Science:

Health Economics
Pharmaceutical Policy
Outcomes Research

Background:

Pharmacoeconomics is increasingly influential in pharmaceutical policy.
Cost-utility analysis is a sophisticated method evaluating drug value.
Current analyses lack standardization, hindering comparability.

Purpose of the Study:

To introduce Value-based Medicine (VBM) as a standardized cost-utility analysis.
To enable consistent comparison of pharmacoeconomic data.
To facilitate rational decision-making in healthcare.

Main Methods:

Standardization of cost-utility analysis variants.
Integration of patient value (quality/length of life) and financial value.
Application of the Value-based Medicine (VBM) system.

Related Experiment Videos

Main Results:

VBM cost-utility analysis ensures comparability between studies.
The VBM system provides a rational methodology for assessment.
Quantification and comparison of patient and financial value are improved.

Conclusions:

Standardized cost-utility analysis via VBM enhances pharmacoeconomic evaluation.
VBM allows for rational quantification and comparison of drug value.
This methodology supports informed decisions in pharmaceutical use.