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Updated: Mar 31, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
Published on: January 12, 2018
Haemoglobin content modulated deformation dynamics of red blood cells on a compact disc
Shantimoy Kar1, Uddipta Ghosh, Tapas Kumar Maiti
1Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, Kharagpur-721302, India. suman@mech.iitkgp.ernet.in.
Abstract:
We investigate the deformation characteristics of red blood cells (RBCs) on a rotating compact disc platform. Our study brings out the interplay between haemoglobin content and RBC deformability in a centrifugally actuated microfluidic environment. We reveal that RBC deformations follow the similar trend of principal stress distributed throughout the radial direction, rendering an insight into the mechano-physical processes involved. This study can be used as a diagnostic marker to determine haematological disorders in diseased blood samples tested on compact disc based microfluidic platforms.
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