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Published on: September 10, 2013
Preparation of Silicon-Carbon-Based Dots@Dopamine and Its Application in Intracellular Ag(+) Detection and Cell
Yuliang Jiang1, Zhaoyin Wang1, Zhihui Dai1
1Jiangsu Collaborative Innovation Center of Biomedical Functional Materials and Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University , Nanjing 210023, P. R. China.
Abstract:
A novel nanocomposite, silicon-carbon-based dots@dopamine (Si-CDs@DA) was prepared using (3-aminopropyl) triethoxysilane, glycerol, and dopamine as raw materials via a rapid microwave-assisted irradiation. This type of Si-CDs@DA exhibited ultrabright fluorescence emission (quantum yield of 12.4%) and could response to Ag(+) selectively and sensitively. Moreover, the obtained Si-CDs@DA can be further applied in sensing intracellular Ag(+) and cell imaging, because of its photostability, salt stability, and low cytotoxicity. This study provides a simple and efficient approach for preparing novel Ag(+) fluorescent probes, which could expand the application of carbon nanomaterials in designing related biosensors.
