Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Cells and Tissue01:30

Bone Cells and Tissue

8.5K
Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
8.5K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.8K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.8K
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

7.0K
Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
7.0K
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

4.3K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
4.3K
Bonding in Metals02:32

Bonding in Metals

52.6K
Metallic bonds are formed between two metal atoms. A simplified model to describe metallic bonding has been developed by Paul Drüde called the “Electron Sea Model”. 
52.6K
Metallic Solids02:37

Metallic Solids

20.8K
Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
20.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating synergistic effects in Co-prolysis of groundnut shell and waste tyres on product distribution under different blend ratios.

Scientific reports·2026
Same author

Corrigendum to "Fabrication of PCL/PVP Electrospun Fibers loaded with Trans-anethole for Bone Regeneration in vitro" [Colloids Surf. B Biointerfaces 171 (2018) 698-706].

Colloids and surfaces. B, Biointerfaces·2026
Same author

Evaluation of chrysin incorporated chitosan-based scaffold for bone regeneration in rat models.

Journal of Indian Society of Periodontology·2025
Same author

Emerging Paradigms in Preventive Dentistry: A Review of Nonfluoridated Remineralizing Agents.

International journal of clinical pediatric dentistry·2025
Same author

MicroRNA‑4327 regulates TGF‑β1 stimulation of matrix metalloproteinase‑13 expression via CREB‑binding protein‑mediated Runx2 acetylation in human osteoblasts.

Experimental and therapeutic medicine·2024
Same author

Erratum to: A hybrid thyroid tumor type classification system using feature fusion, multilayer perceptron and bonobo optimization.

Journal of X-ray science and technology·2024
Same journal

Effect of Porous Zirconia Coating on Human Gingival Fibroblasts and Its Mechanism.

Journal of biomedical nanotechnology·2022
Same journal

Research on Mechanism of Nanometric Bone Pulp Activated with Double Gene as Bone Morphogenetic Protein 1 and Vascular Endothelial Growth Factor for Improving the Strength of Centrum in Osteoporosis.

Journal of biomedical nanotechnology·2022
Same journal

Carrier-Free Nanomedicine for Cancer Immunotherapy.

Journal of biomedical nanotechnology·2022
Same journal

Cyclovirobuxine D Brain-Targeted Liposomes Improve Cerebral Ischemia-Reperfusion Injury via Anti-Oxidant Stress and Activating Autophagy.

Journal of biomedical nanotechnology·2022
Same journal

Protective Effect of Iron Oxide Nanoparticles on Periodontal Injury in Rats by Inhibiting Collagenase-1 and Alkaline Phosphatase Expression.

Journal of biomedical nanotechnology·2022
Same journal

Targeting the Conserved Sequence of the Substrate for the Proteinase of Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2) Using Nano-Networks: Efficacy, Stability, and No Cytotoxicity.

Journal of biomedical nanotechnology·2022
See all related articles

Related Experiment Video

Updated: Feb 9, 2026

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
09:49

Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

Published on: February 23, 2024

2.7K

Metallic Nanomaterials for Bone Tissue Engineering.

S Dhivya, J Ajita, N Selvamurugan

    Journal of Biomedical Nanotechnology
    |October 28, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Metals are increasingly used in bone tissue engineering for their mechanical strength and ability to accelerate bone regeneration. Surface modifications enhance their bioactivity, promoting better bone healing outcomes.

    More Related Videos

    Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
    07:14

    Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

    Published on: July 27, 2022

    4.2K
    Experimental Approaches to Tissue Engineering
    16:41

    Experimental Approaches to Tissue Engineering

    Published on: August 29, 2007

    6.8K

    Related Experiment Videos

    Last Updated: Feb 9, 2026

    Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering
    09:49

    Author Spotlight: Insights into the Use of Apple-Derived Cellulose Scaffolds for Bone Tissue Engineering

    Published on: February 23, 2024

    2.7K
    Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
    07:14

    Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

    Published on: July 27, 2022

    4.2K
    Experimental Approaches to Tissue Engineering
    16:41

    Experimental Approaches to Tissue Engineering

    Published on: August 29, 2007

    6.8K

    Area of Science:

    • Biomaterials Science
    • Orthopedic Research
    • Tissue Engineering

    Background:

    • Conventional bone grafting is being superseded by tissue engineering using 3D biomimetic materials.
    • Metals offer superior mechanical strength and possess inherent properties beneficial for bone regeneration.

    Purpose of the Study:

    • To review the biological roles of key metals (Zn, Ti, Zr, B, Sr, Mg, Ag, Cu) in bone regeneration.
    • To discuss metal surface modifications for enhanced bioactivity and bone healing.

    Main Methods:

    • Literature review of recent scientific publications.
    • Analysis of the biological functions of selected metals in bone formation and regeneration.
    • Examination of surface modification techniques for metallic biomaterials.

    Main Results:

    • Metals act as enzyme cofactors, stimulate angiogenesis, enhance extracellular matrix synthesis, and promote bone formation while inhibiting resorption.
    • Metals exhibit inherent osseointegration, osteoconductivity, and antimicrobial properties.
    • Surface modifications significantly improve the bioactivity and bone regeneration potential of metallic biomaterials.

    Conclusions:

    • Metals are crucial biomaterials for advanced bone tissue engineering due to their multifaceted biological roles.
    • Surface engineering of metallic implants is a key strategy for optimizing bone regeneration and clinical outcomes.