Related Experiment Video
Updated: Mar 31, 2026
Crystallization and Structural Determination of an Enzyme:Substrate Complex by Serial Crystallography in a Versatile Microfluidic Chip
Published on: March 20, 2021
Design of Enzyme-Encapsulated Protein Containers by In Vivo Crystal Engineering
Satoshi Abe1, Hiroshi Ijiri1, Hashiru Negishi1
1Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta-cho, 4259-B55, Midori-ku, Yokohama, 226-8501, Japan.
Abstract:
Crystalline protein assemblies of polyhedra crystal (PhC) can be utilized as solid enzyme containers for long-term storage of enzymes with retention of their enzymatic activity. The enzymes can be released from the crystals at the optimum pH for the enzymatic activity by dissolution of the crystals using in vivo crystal engineering.
