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Related Experiment Video

Updated: Mar 31, 2026

Semi-automated Biopanning of Bacterial Display Libraries for Peptide Affinity Reagent Discovery and Analysis of Resulting Isolates

Semi-automated Biopanning of Bacterial Display Libraries for Peptide Affinity Reagent Discovery and Analysis of Resulting Isolates

Published on: December 6, 2017

BDB: biopanning data bank.

Bifang He¹, Guoshi Chai¹, Yaocong Duan¹

¹Center of Bioinformatics (COBI), Key Laboratory for NeuroInformation of Ministry of Education, University of Electronic Science and Technology of China, Chengdu 610054, China.

Nucleic Acids Research

|October 28, 2015

Summary

This summary is machine-generated.

The Biopanning Data Bank (BDB) is an updated resource for combinatorial peptide library biopanning results. It now includes enhanced data and tools, improving its utility for phage display researchers.

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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

Area of Science:

Biotechnology
Bioinformatics
Molecular Biology

Background:

The Biopanning Data Bank (BDB) is an updated version of the MimoDB database.
It serves as a central portal for biopanning results from combinatorial peptide libraries.

Purpose of the Study:

To enhance the BDB database with updated biopanning data and improved functionalities.
To provide a comprehensive resource for researchers utilizing phage display technology.

Main Methods:

Data compilation from 1322 peer-reviewed papers, including 2904 biopanning datasets.
Revisiting stored data to add peptide affinity, measurement methods, and procedures for 2298 peptides.
Implementation of a new user-friendly web interface, help system, data visualization, and analysis tools.

Main Results:

BDB now contains 25,786 peptide sequences, 1704 targets, 492 templates, 447 peptide libraries, and 310 crystal structures.
Detailed affinity and experimental information added for a significant portion of the peptide data.
Enhanced web interface and integrated analysis tools improve data accessibility and usability.

Conclusions:

The updated BDB database offers a significantly improved resource for the biopanning and phage display scientific communities.
The new features are expected to enhance research efficiency and discovery in peptide-target interactions.
BDB aims to be a major resource for scholars in the field.