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Updated: Mar 31, 2026

On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis
Published on: May 31, 2020
MR Spectroscopic Profile of an Angiocentric Glioma
Matthew T Whitehead1, Gilbert Vezina2
1Department of Radiology, Children's National Medical Center, Washington, DC, U.S.A. matthewthomaswhitehead@gmail.com.
Abstract:
A 2-year-old female with focal motor seizures was referred to our Center for brain MRI. Imaging revealed a non-enhancing, demarcated, cortically-based mass lesion in the right superior frontal gyrus and cingulate gyrus. Single voxel MR spectroscopy through the tumor showed markedly elevated myoinositol and/or glycine, mildly elevated choline, and moderately decreased N-acetyl aspartate. Histological assessment of the lesion following gross total resection was diagnostic of an angiocentric glioma. Herein, we present the first illustration of MR spectroscopic findings from a typical angiocentric glioma.

