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Updated: Mar 31, 2026
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Published on: September 5, 2017
FDG PET/CT Findings in Multiple Splenic Amebomas (Amebic Granulomas)
Aisheng Dong1, Yang Wang, Changjing Zuo
1From the Departments of *Nuclear Medicine and †Pathology, Changhai Hospital; and ‡Department of Microbiology and Parasitology, Second Military Medical University, Shanghai, China.
Abstract:
Splenic ameboma (amebic granuloma) is rare. A 38-year-old man with a severe pneumonia due to inhalation of swimming pool water 18 months ago complained of night sweat, tiredness, and anorexia for 1 month. Abdominal ultrasound showed multiple nodules in the spleen. These nodules showed slight enhancement on enhanced CT and intense FDG uptake on PET/CT. Splenectomy was performed. Multiple splenic amebomas were confirmed by pathology. Free-living amoebae were also detected in samples of pleural effusion and blood. Splenic ameboma, although rare, should be included in the differential diagnosis with isolated focally increased FDG activity in the spleen.
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