Endometriosis Under Estradiol Stimulation Imaged Using 18F-FDG and Its Control After Estradiol Cessation and
Frédéric Arsenault1, Éric Turcotte
1From the *Department of Nuclear Medicine, Centre Hospitalier Universitaire de Montréal (CHUM), Hôpital Hôtel-Dieu de Montréal, Montréal; and †Sherbrooke Molecular Imaging Center (CIMS), Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Abstract:
Endometriosis is a frequent and benign cause of disabling abdominal pain, for which a diagnosis suspicion is clinically raised, but its confirmation necessitates a surgical exploration by laparoscopy. Foci of endometriosis proliferate under estrogen stimulation, like normal endometrium. We present a patient under estradiol stimulation for a history of endometrial cancer who underwent a PET/CT scan to assess an abdominal lesion showing a high F-FDG uptake, which normalized under progesterone hormonal replacement and cessation of estradiol. Two consecutive biopsies confirmed endometriosis. F-FDG evaluation of endometriosis under estrogen stimulation could be a promising approach to refractory endometriosis assessment.
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