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Updated: Mar 31, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
DENGUE WITH CENTRAL NERVOUS SYSTEM INVOLVEMENT
Abstract:
Dengue has spread to new geographic areas affecting both children and adults, and it has become a global threat. Dengue with central nervous system involvement includes febrile seizures, encephalopathy, encephalitis, aseptic meningitis, intracranial hemorrhages, intracranial thrombosis, subdural effusions, mononeuropathies, polyneuropathies, Guillain-Barré syndrome, and transverse myelitis. These manifestations may be associated with co-infections, co-morbidities, or complications of prolonged shock. It is important to consider dengue as a cause for the above neurological presentations, particularly in endemic territories for dengue disease.
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